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Objectives : This paper summarizes effective waste management and disposal methods for plastic and medical wastes during the prolonged COVID-19 pandemic.Methods : We reviewed the literatures reporting and identifying the current status and characteristics of wastes related to COVID-19, and the management and treatment guidelines for those wastes. We also investigated various technologies for waste treatment and disposal, and assessed the current status and future direction of the technologies in Korea.Results and Discussion : In the first half of 2020 in Korea, the amount of plastic waste produced had increased by 15.6% year-on-year, and medical waste production also increased significantly from 0.6 ton in January 2020 to 2,928 ton in August 2021. All of the infectious wastes are currently being incinerated in Korea, but there are concerns on air pollutant emissions and insufficient treatment facilities. Municipal solid waste also suffers from a lack of landfill capacity and low price competitiveness in the recycling industry.Conclusions : Policy and system need to be improved to reduce the infectious waste generation from the sources, and treatment and disposal technologies for produced wastes also need to be developed. Furthermore, hospitals and health care facilities should establish their own waste reducing systems which may include chemical treatment and sterilization units.