Correspondencewith 95 per cent confidence limits of 1.78 and 10.48 and has a highly significant association with the presence of peritonitis, P < 0.001,We have recently published' data on 1204 consecutive patients admitted to hospital with right lower quadrant pain, and identified rebound tenderness as an important predictor of acute appendicitis with an odds ratio of 3.36 and P < 0.001. Of importance, in a multiple

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A man with a history of pancreatitis was given aprotinin intravenously just before endoscopic retrograde pancreatography. Despite negative sensitivity tests with aprotinin eye drops he developed a profound anaphylactic reaction on intravenous administration of the drug.Ocular sensitivity tests may not predict severe anaphylactic reactions to intravenous aprotinin.

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