A field experiment was carried out to determine the best effect of Johnson grass extract, alone or in combination with Quizalofop-p-Tefuryl herbicide, to achieve the benefit of their integration into weed control programs to reduce reliance on herbicides in controlling weeds, increasing yield and reducing environmental pollution by these herbicides. The randomized complete block design (RCBD) with the split plot arrangement by three replicates was applied, the distance between the rows (20, 25 and 30 cm) represents the main plots. The control treatments : weed-free (T1), application Quizalofop-p-Tefuryl at rate 2 ml/l (T2), Johnson grass extract at rate 18 l/ha (T3), half herbicide amount + half extract amount (T4) and weedy treatment (T5) , represent the sub-plots . The results showed that of distance 20 cm achieved lowest density of companion weeds (52.20 weeds/m2) and highest percentage of weed control (50.42) after 60 days of application, and highest seed yield, oil yield reached 1.781 and 0.675 t/ha, respectively. The distance 30 cm achieved highest number of capsules (14.790 capsules/plant) seeds (8.337 seeds/capsule) and highest weight of 1000 seeds reaching 7.379 g. Application of Quizalofop-p-Tefuryl (T2) achieved lowest weed density (54.78 weeds/m2), highest weed control percentage (52.22) after 60 days of application. Besides, highest number of capsules (14.956 capsules/plant), seeds were (8.580 seeds/capsule), highest weight of 1000 seeds was 7.611 g, and highest seed yield , oil yield reached 1.779 and 0.7113 t/ha, respectively. Distance 20 cm with treatment (T2) achieved lowest number of weeds reaching (44.67 weeds/m2), highest percentage of weed control (57.59) after 60 days of application, highest seed yield, oil yield reached 2.067 and 0.7267 t/ha, respectively. Distance 30 cm and treatment (T2) achieved highest number of capsules (16.05 capsules/plant), seeds (8.580 seeds/capsule) and highest weight of 1000 seeds reaching 7.873 g.