The pharn~acodynamics and pharmacokinelics oJ" a new nondepolarizing neuromuscular blocking agent, Ore 9426, were investigated. Ten patients undergoing elective head and neck surgery and anaesthetized with nitrous oxide', halothane and fentanyl, received a bolus dose of Ore 9426 (I rag. kg -t , 3 x EDgo

The session-to-session variation in URR and Kt/V is small in stable hemodialysis patients. Nevertheless, the averaged value of two to three measurements is required to assess the dose of dialysis reliably. Assessment of dietary intake requires at least three PCR measurements or food records for at least one week. Basing clinical decisions on a single dialysis adequacy assessment is an unjustified practice that should be abandoned.

These observations suggest that the contradiction of a stable body mass over time despite an apparently insufficient DEI in haemodialysis patients is mainly explained by an underestimation of habitual DEI from self-reported food intake.

No abstract

Prescribing a HP diet resulted in a modest increase in actual protein intake, but increasing dialysis dose did not have a contributing effect. A HP diet or increasing the dialysis dose did not have a favourable effect on the nutritional status. A dietary protein intake of at least 0.9 g/kg IBW/day appears to be sufficient for adequately dialysed haemodialysis patients without overt malnutrition.