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The prognosis for patients with high-grade glioma is poor despite aggressive multimodal treatment. About 90% of these lesions recur intracranially. The frequency of spinal cord disease is less than 2%. We report two cases of high-grade glioma with spinal drop metastases. One of the learning points we want to share is to think in the possibility of spinal cord metastases from brain gliomas. When symptoms are suggestive of spinal cord compromise, spine MRI should be done.

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