Novel nano-materials, nano-cellulose containing reactive polyhedral oligomeric silsesquioxanes with multi-N-methylol (R-POSS), were used for adsorption reactive dyes from dyeing wastewater solution. Langmuir isotherm mathematical model and Freundlich nonlinear isotherm model on the nano-cellulose were analyzed. Two reactive dyes, Reactive Yellow B-4RFN, Reactive Blue B-RN, were used in this study. The results showed that the adsorption capacity of nano-cellulose for reactive dyes was significantly higher than that of control cellulose.i