Actinomycetes, which can produce a variety of bioactive compounds in the metabolic process, is one of the important sources of novel drugs, enzymes, anti-tumor drugs and enzyme inhibitors. It has been the focus of researchers to find and develop Actinomycetes with special characters. Strain XJ-16 is a blue alkali-resistant filamentous bacterium with high antimicrobial activity isolated from saline-alkali land of Xinjiang. Based on the classification, the enzyme production, metabolite antibacterial activity, and antibacterial substance isolation of XJ-16 were explored. which showed that XJ-16 belongs to the blue group of Streptomyces sp, and it can secrete cellulase, lipase, urease, protease, catalase and oxidase during metabolism. In addition, the bacteriostatic substance secreted by the strain XJ-16 showed inhibitory effects against both Gram-positive and Gram-negative bacteria, as well as the yeast Candida albicans. Then it was found that the bacteriostasis produced by XJ-16 has strong tolerance to acid, weak tolerance to alkali, and easy to be inactivated. After tested by HPLC, the retention time of antimicrobial substance was 13.261 min. This study provides a theoretical basis for the search for new antibacterial compounds and the further development of blue alkaline Actinomycetes XJ-16.

The purpose of this paper is to investigate the current situation of community mental health services in Hunan Province. At the same time, this paper can also provide the corresponding basis for community health services. In the era of large data technology so popular, for the survey of mental health, we can use the technology of large data analysis to conduct the questionnaire survey of community mental health services, and conduct random sampling of community residents. The results of this survey include the degree of community residents’ understanding of mental health, the influencing factors of psychological help seeking, the utilization of psychological service resources, the expected charges and the corresponding equipment. According to the results of the questionnaire survey, we can see that the psychological health service needs of residents in Hunan communities are affected by the level of regional economic development, economic and social status, the quality of professional resources and the support attitude of the government.

No abstract