In order to address water damage of asphalt pavement, reduce the occurrence of water-related potholes, deformation, and other diseases, and improve the performance and service life of the pavement, a nano-TiO2 superhydrophobic coating (PSC) on asphalt pavement was prepared from waterborne polyurethane and nano-TiO2 modified by stearic acid. FT-IR measured stearic acid successfully modified low surface energy substance on the surface of nano-TiO2. The SEM image shows that the PSC has a rough surface structure. The contact angle and rolling angle of the PSC in the contact angle test are 153.5° and 4.7°, respectively. PSC has a super-hydrophobic ability, which can improve the water stability of the asphalt mixture. Although the texture depth and pendulum value have been reduced by 2.5% and 4.4%, respectively, they all comply with the standard requirements. After the abrasion resistance test, the PSC coating still has a certain hydrophobic ability. These results surface PSC coating can effectively reduce water damage on asphalt pavement, and has considerable application value.