Background Spindle cell hemangioma (SCH) was an extremely rare benign tumor which typically arised in the subcutis of the distal extremities of young people. In this study, we reported a case of multiple spindle cell hemangioma in both lungs. Case presentation A 19-year-old HIV-negative female was found to have multiple lung nodules by the chest X-ray during the physical examination. Her chest CT scan revealed multiple round-like pulmonary nodules in both lungs. Based on the morphological features and immunohistochemical examination for vascular markers CD31, CD34 and D2–40, the mass was diagnosed as SCH after surgery. Conclusion SCH was an extremely rare tumor especially in both lungs. It should be considered in differential diagnosis of multiple lung nodules. Pathological features, the expression of CD31, CD34 and D2–40 could help to diagnosis of SCH.

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Objective: This study aims to identify the difference between patients who have been diagnosed with either intralobar sequestration (ILS) or extralobar sequestration (ELS).Methods: In this clinical study, 29 children with pulmonary sequestration (PS), diagnosed via physical examination and imaging at our hospital between January 2019 and January 2020, were enrolled. We compared whether statistical differences existed in the blood loss, operative time, and post-operative hospital stay between the two groups (ILS and ELS) after thoracoscopic pulmonary wedge resection.Results: There were no significant differences in gender, operative age, preoperative weight, and isolated lung position between the ILS and ELS groups (p > 0.05). There was significantly more intra-operative bleeding in children with ILS than those with ELS (p < 0.05), and the operation time and postoperative hospitalization times were significantly longer for those with ILS(p < 0.05). Upon microscopic evaluation after surgery, we found the appearance of ILS and ELS to be similar.Conclusion: Different types of congenital PS have different influences onnewborns during and after operation. For children with ILS, surgery is more difficult and the postoperative recovery is slower than for children with ELS. For this reason, we suggest that more attention should be paid to the clinical treatment of children with ILS. Although ILS and ELS present with different manifestations, we found no evidence of a significant difference in the postoperative microscopy of the two conditions.