HighlightsApoferritin improved MPTP-induced motor deficits.Apoferritin rescued dopaminergic neurodegeneration in the SN of MPTP-treated mice.
Apoferritin inhibited MPTP-induced iron aggregation.Apoferritin prevented MPTP-induced ferroptosis by regulation of ACSL4 and FSP1.
Four enantiomeric pairs of highly modified spirocyclohexenone neolignans, (±)-pinnatifidaones A–D, with a novel 2-oxaspiro[4.5]deca-6-en-8-one motif, were isolated from Crataegus pinnatifida.
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