Aiming at some uncertainty problems such as quality inspection of adhesive structure and risk assessment in the practical engineering application, a possibility estimation model is established. Firstly, according to the fuzziness, randomness and uncertainty of the measurement data, a transformation method of possibility distribution with non-single peak values and nonlinearity is proposed from probability density function. Secondly, for possibility distributions of measurement data of each sensor, a kind of possibility fusion rules is put forward, then the fusion distribution is estimated by the possibility mean. Finally the model is applied to the mechanical property estimation of adhesive structure, and the result forecasts the quality. The proposed model with strong applicability, not only provides convenience for the operations among possibility distributions, but also offers new ideas and new methods to deal with uncertain problems.

Abstract. As an important part of chromatography instruments, chromatographic column plays an important role in the progress of science and the development of production. In order to avoid the traditional process ,design -processing-test -Fixed design -re-processing and effectively shorting the design cycle save a lot of manpower, material and financial resources. This paper offers to watch the changes of flow profile within the column by the application of simulation software ANSYS CFX .Besides, according to the distribution of flow profile, the traditional column has been done a lot of dynamic simulation, especially the stigma part of the column. From a fluid Machinery perspective, we simulated and designed the structure, and then found out the best separation efficiency of the column structure.