The high pace of economic growth has posed many challenges. These challenges include depletion of natural resources, globalization challenges, and environmental degradation. The Middle East and North Africa (MENA) economies are rich in mineral resources. Economic globalization has put the MENA countries in the spotlight for the developed world. Despite the status of being a hotspot for mineral resource richness, there is limited research on the effect of natural resources and economic globalization on the environmental degradation of the MENA countries. This paper examines the effects of natural resource abundance and economic globalization on environmental quality by considering trade openness, urbanization, and economic growth from the year 1980 to 2018. We apply second-generation panel cointegration techniques along with continuously updated fully modified (Cup-FM) and continuously updated bias-corrected (Cup-BC) techniques. The findings show that natural resource abundance significantly improves environmental quality. Likewise, economic globalization also mitigates emissions levels in the MENA countries. In contrast, trade openness, urbanization, and economic growth significantly deteriorate environmental quality. The unidirectional link indicates natural resources and economic globalization create trade openness. The paper provides novel empirical evidence and policy recommendations for sustainable development goals.
Purpose
To compare the treatment efficacy between repeated low-level red light (RLRL) therapy and 0.01% atropine eye drops for myopia control.
Methods
A single-masked, single-center, randomized controlled trial was conducted on children 7 to 15 years old with cycloplegic spherical equivalent refraction (SER) ≤ −1.00 diopter (D) and astigmatism ≤ 2.50 D. Participants were randomly assigned to the RLRL group or low-dose atropine (LDA, 0.01% atropine eye drops) group and were followed up at 1, 3, 6, and 12 months. RLRL treatment was provided by a desktop light therapy device that emits 650-nm red light. The primary outcome was the change in axial length (AL), and the secondary outcome was the change in SER.
Results
Among 62 eligible children equally randomized to each group (31 in the RLRL group, 31 in the LDA group), 60 children were qualified for analysis. The mean 1-year change in AL was 0.08 mm (95% confidence interval [CI], 0.03–0.14) in the RLRL group and 0.33 mm (95% CI, 0.27–0.38) in the LDA group, with a mean difference (MD) of −0.24 mm (95% CI, −0.32 to −0.17;
P
< 0.001). The 1-year change in SER was −0.03 D (95% CI, −0.01 to −0.08) in the RLRL group and −0.60 D (95% CI, −0.7 to −0.48) in the LDA group (MD = 0.57 D; 95% CI, 0.40–0.73;
P
< 0.001). The progression of AL < 0.1 mm was 53.2% and 9.7% (
P
< 0.001) in the RLRL and LDA groups, respectively. For AL ≥ 0.36 mm, progression was 9.7% and 50.0% (
P
< 0.001) in the RLRL and LDA groups, respectively.
Conclusions
In this study, RLRL was more effective for controlling AL and myopia progression over 12 months of use compared with 0.01% atropine eye drops.
Translational Relevance
RLRL therapy significantly slows axial elongation and myopia progression compared with 0.01% atropine; thus, it is an effective alternative treatment for myopia control in children.
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