High energy density Li2MnO3 is fully activated by F-substitution by decreasing the grain size and improving the Li+ diffusion kinetics.

This study investigated monthly variations of surface urban heat island intensity (SUHII) and the applicability of the local climate zones (LCZ) scheme for land surface temperature (LST) differentiation within three spatial contexts, including urban, rural and their combination, in Shenyang, China, a city with a monsoon-influenced humid continental climate. The monthly SUHII and LST of Shenyang were obtained through 12 LST images, with one in each month (within the period between 2018 and 2020), retrieved from the Thermal InfraRed Sensor (TIRS) 10 in Landsat 8 based on a split window algorithm. Non-parametric analysis of Kruskal-Wallis H test and a multiple pairwise comparison were adopted to investigate the monthly LST differentiations with LCZs. Overall, the SUHII and the applicability of the LCZ scheme exhibited spatiotemporal variations. July and August were the two months when Shenyang underwent strong heat island effects. Shenyang underwent a longer period of cool than heat island effects, occurring from November to May. June and October were the transition months of cool–heat and heat–cool island phenomena, respectively. The SUHII analysis was dependent on the definition of urban and rural boundaries, where a smaller rural buffering zone resulted in a weaker SUHI or surface urban cool island (SUCI) phenomenon and a larger urban area corresponded to a weaker SUHI or SUCI phenomenon as well. The LST of LCZs did not follow a fixed order, where in July and August, the LCZ-10 (Heavy industry) had the highest mean LST, followed by LCZ-2 (Compact midrise) and then LCZ-7 (Lightweight low-rise). In comparison, LCZ-7, LCZ-8 (Large low-rise) and LCZ-9 (Sparsely built) had the highest LST from October to May. The LST of LCZs varied with urban and rural contexts, where LCZ-7, LCZ-8 and LCZ -10 were the three built LCZs that had the highest LST within urban context, while LCZ-2, LCZ-3 (Compact low-rise), LCZ-8, LCZ-9 and LCZ-10 were the five built LCZs that had the highest LST within rural context. The suitability of the LCZ scheme for temperature differentiation varied with the month, where from July to October, the LCZ scheme had the strongest capability and in May, it had the weakest capability. Urban context also made a difference to the suitability, where compared with the whole study area (the combination of urban and rural areas), the suitability of built LCZs in either urban or rural contexts weakened. Moreover, the built LCZs had a higher level of suitability in an urban context compared with a rural context, while the land-cover LCZs within rural had a higher level of suitability.

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BackgroundInorganic arsenic (iAs) is a well-known human carcinogen recognized by the World Health Organization and the International Agency for Research on Cancer. Currently, most iAs studies in populations are concerned with drinking water and occupational arsenicosis. In Guizhou province, arsenicosis caused by the burning of coal in unventilated indoor stoves is an unusual type of exposure. Because the poisoning mechanism involved in arsenicosis is as yet unknown and no effective therapy exists, progress has been slow on the prevention and therapy of arsenicosis.ObjectivesWe examined the relationship between arsenic (As) exposure from the burning of coal in unventilated indoor stoves and genetic damage in humans, using cellular and molecular indices. We selected villagers from Jiaole township, Guizhou province, China, who had been exposed to milligram levels of As daily via food and air contaminated by the burning of As-containing coal in unventilated indoor stoves.ResultsThe As-exposed subjects from Jiaole were divided into four groups according to skin lesion symptoms: nonpatients, mild, intermediate, and severe arsenicosis. Another 53 villagers from a town 12 km from Jiaole were recruited as the external control group. In the four groups of exposed subjects, As concentrations in urine and hair were 76–145 μg/L and 5.4–7.9 μg/g, respectively. These values were higher than those in the external control group, which had As concentrations of 46 μg/L for urine and 1.6 μg/g for hair. We measured sister chromatid exchange and chromosomal aberrations to determine human chromosome damage, and for DNA damage, we measured DNA single-strand breaks and DNA–protein cross-links. All measurements were higher in the four exposed groups compared with the external control group. DNA repair was impaired by As exposure, as indicated by the mRNA of O-6-methylguanine-DNA methyltransferase (MGMT), X-ray repair complementing defective repair in Chinese hamster cells 1 (XRCC1), and, to a lesser extent, by the mismatch repair gene hMSH2 mRNA. The expression of mutant-type p53 increased with aggravation of arsenicosis symptoms, whereas the expression of p16-INK4(p16) decreased. p53 mutated at a frequency of 30–17% in the carcinoma (n = 10) and precarcinoma (n = 12) groups. No mutation was found in p16, although deletion was evident. Deletion rates were 8.7% (n = 23) and 38.9% (n = 18) in noncarcinoma and carcinoma groups, respectively.ConclusionsThe results showed that long-term As exposure may be associated with damage of chromosomes and DNA, gene mutations, gene deletions, and alterations of DNA synthesis and repair ability.

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