In current urban regeneration, the conservation and reuse of traditional village space are significant measures to activate urban-rural development. Traditional villages in the Jiangnan region of eastern China represent the typical vernacular culture of urban-rural settlements, which affects the dynamic development of urban regeneration. Aiming at the disadvantages of the decentralization of research objects and the simplification of spatial characteristics in the research of traditional villages in the Jiangnan region, this paper will construct the spatial pedigrees of villages. This study takes 728 traditional villages in the Jiangnan region as cases. First, through on-site research, the spatial pattern of villages in isolated areas was mapped and drawn. Then, on the basis of on-site review, this study labeled the village space, summarized village space information, and used ArcGIS and BIM to create a 3D model of the village. In ArcGIS platform through SOA to establish criterion framework for recognizing the types of village pedigree. . Finally, the classification of villages was spatially visualized, and a pedigree was constructed according to the type context. The research result indicates： (1) The aggregation mode of traditional villages in the south of the Jiangnan region presents the characteristics of local aggregation and partial dispersion, which are directly affected by factors such as elevation, water system, and road system. (2) Analysis of the spatial pedigrees of traditional villages through spatial types and spatial growth patterns revealed four pedigree types, including spatial environment pedigree, the spatial organization pedigree, spatial morphological pedigree, and architectural form pedigree. (3) The pedigree shows and distinguishes independent developmental context and evolved form, presenting an extended pattern of prototypes and sub-types.

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The global spread of the COVID-19 has given severely challenge to the contemporary human settlement environment. Traditional villages, as an essential human settlement, which has been significant in contemporary life. This article takes the traditional village space in the Jiangnan region, China as an example to analyse the positive interaction between humans and nature, health, and space in its traditional design. This research points out that in the traditional village space, healthy human settlements have two levels: “material form” and “internal sprite”. In addition to focusing on the transformation, innovation, and application of the technology, designers should exceed the material level to seek non-material dialogue and integration, to explore the important role of inner spiritual art for healthy living. Finally, this research combine with the urban epidemic prevention function and pointed out that the symbiosis mechanism between urban and rural areas should be actively explored. The penetration and integration of urban and rural areas can better cure, and promote the sustainable protection, activation, utilization and innovation of traditional villages in the future.