Industrial structure upgrading is of great significance to continuous growth of economy, establishing Free Trade Zones(FTZs) as an important space-oriented industrial policy space carrier, leading regional industrial structure upgrade .This paper uses panel data from 31 provinces (autonomous regions and municipalities) in mainland China from 2000 to 2015, makes an empirical analysis of the industrial structure upgrading effect of FTZs, it is found that the rationalization effect of the industrial structure of China's free trade zone is significant, the effect of advanced industrial structure is not significant; In the east, the rationalization effect of the industrial structure of the free trade zone is significant, in the Midwest, the industrial structure of the free trade zone has a significant effect on the advanced nature.
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