Uniformly sized microspheres of poly(d, l-lactic-co-glycolic) (PLGA) encapsulating tamoxifen(TAM) were successfully prepared by solvent evaporation. In this study three different polylactide-co-glycolides were used with differing lactide-glycolide ratios (50:50, 75:25, and 85:15, respectively). The sphere size distribution and morphology was analyzed using Laser Particle Size Analyzer and SEM. The drug loading and release in vitro of the microspheres were also investigated. The result showed that the microspheres have good spherical and better sustained release.

Abstract. With the deepening reform of China's economic system and the promotion of financial innovation, Internet finance has been rising. Today, Internet finance, including crowd-funding, P2P, securities, Internet banking, financial holding company, third-party payment, etc.

Engineering education plays an irreplaceable role in the process of national industrialization. The "Excellent Engineer Training Program" is also an important measure to promote our country change from a big country of engineering education to a powerful country of Engineering education. In this context, the reality is that many students have poor practical ability to solve practical engineering problems and lack of systematic view. Therefore, how to strengthen the design of teaching content and cultivate innovative engineering and technical talents with high quality, strong foundation, strong ability and wide adaptability has become a realistic and urgent problem in teaching reform. "Comprehensive Design of Automation Technology" is an indispensable link to test the professional technical knowledge reserve of students majoring in automation and to improve their personal ability, team ability and overall consciousness. Based on summarizing the shortcomings of previous design contents, this paper puts forward three reform schemes, which have achieved better results in the actual teaching process. It can be used for reference.

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