Human papillomavirus (HPV) infection is a common sexually transmitted disease worldwide and the leading cause of cervical cancer. Current vaccines do not cover all HPV genotypes whereas the distribution of HPV genotypes varies in different geographic regions. The study aimed to investigate the distribution of HPV genotypes in patients with cervical squamous intraepithelial lesion (SIL) and cervical squamous cell carcinoma (SCC) in Taizhou City of Jiangsu Province, China. A total of 940 patients including 489 cases with cervical low-grade squamous intraepithelial lesions (LSIL), 356 cases with cervical high-grade squamous intraepithelial lesions (HSIL), and 95 cases with cervical SCC, underwent a biopsy or surgery in Taizhou People's Hospital between January 2019 and December 2019. The HPV testing results were retrospectively analyzed. The overall prevalence of any, high-risk, and low-risk HPV was 83.83%, 81.91%, and 12.13%, respectively. The 5 most common HPV genotypes were HPV16 (35.64%), HPV52 (16.91%), HPV58 (13.94%), HPV33 (8.94%), and HPV18 (7.98%). The prevalence of any and HR-HPV in SCC was significantly higher than those in LSIL and HSIL, while the prevalence of LR-HPV in SCC was significantly lower than those in LSIL and HSIL (
P
< .01). Single and dual HPV infections were prevalent in SCC, LSIL, and HSIL. Furthermore, the prevalence of dual HPV infection in SCC was significantly higher than those in LSIL and HSIL (
P
= .002). The HPV prevalence varied by age, being highest among women with SCC, LSIL, and HSIL aged 40 to 49 years, 40 to 49 years, and 50 to 59 years, respectively. In conclusion, the findings revealed a very high prevalence of HPV in women with cervical lesions in Taizhou. Routine HPV tests must cover all common HPV genotypes in clinical practice.
Under the background of normalization of epidemic prevention and control, how to achieve effective cooperation in a remote office is an urgent problem for organizations. Online communication mainly uses text as the medium. Besides expressing meaning, text also contains the emotions of the transmitter, which has an important impact on the communication and cooperation between two parties. This study starts with the Emotions as Social Information theory (EASI theory) and explores the influence mechanism of emotions of texts on individuals' willingness to cooperate. The results of the experimental study (n=203) found that individuals have higher social perception of the sender of positive texts (i.e. perception of their warmth and competence), so they are more willing to cooperate with them. And social perception plays a partial mediating role in text emotion and willingness to cooperate. The results of this paper reveal the internal mechanism of text emotion promoting cooperation willingness in remote cooperation and provide a new perspective on how to improve cooperation willingness.
Feng Jing is an existing town 1500 years of history of civilization.Through the literature review, this article from the Fengjing Town Tourism site planning and design of these two aspects, some site specific features that make travel sites to attract more tourists.With the advantages of specific functions on its Web site, so that local culture can be more well-known and thus passed along.
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