We propose an active mechanism for coupling the quantized mode of a nanomechanical resonator to the persistent current in the loop of superconducting Josephson junction (or phase slip) flux qubit. This coupling is independently controlled by an external coupling magnetic field. The whole system forms a novel solid-state cavity QED architecture in strong coupling limit. This architecture can be used to demonstrate quantum optics phenomena and coherently manipulate the qubit for quantum information processing. The coupling mechanism is applicable for more generalized situations where the superconducting Josephson junction system is a multi-level system. We also address the practical issues concerning experimental realization.
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