Variability is one of the characteristics of blazars. The rapid variability is superposed on the long term variation. In this work, the variability on different time scales, such as intra-day (IDV), short-term (STV) and long-term (LTV) variations are presented for some sources. We also presented our own observations of some selected objects, for which the historical data were compiled for periodicity analysis using several methods. The parameters of the binary black hole system OJ 287 are determined.