This meta-analysis studied the association between interleukin 2 receptor a (IL2RA) gene polymorphisms rs2104286 and rs12722489 and susceptibility to multiple sclerosis (MS). Case-control genetic association studies published before January 2011 were retrieved from the PubMed and EMBASE databases and the Cochrane Library. Eight studies comprising 13 569 patients and 23 435 controls met the selection criteria for metaanalysis of the IL2RA rs2104286 polymorphism. Using a fixed-effects model, the T allele and the TT and TT + TC genotypes of the IL2RA rs2104286 polymorphism were found to be associated with MS. Five studies comprising 5643 patients and 6415 controls met the selection criteria for meta-analysis of the IL2RA rs12722489 polymorphism. Using a fixed-effects model, the C allele and the CC genotype of the IL2RA rs12722489 polymorphism were found to be associated with MS but the CC + CT genotype was not. It was concluded that both of the IL2RA gene polymorphisms, rs2104286 and rs12722489, were associated with increased susceptibility to MS.

In this research, the leaching and preparation of Al 2 O 3 from retorting residue of Fushun east open-pit oil shale in China were investigated. The optimum acid leaching conditions are the following: activation temperature is 850 ºC, activation time is 1h, the particle size of the raw material is 0.074mm, the concentration of acid is 12%, the liquid to solid ratio is 5:1, reaction temperature is 100 ºC and reaction period is 1.5 h. The homogeneous chemical precipitation method was applied for the preparation of alumina. Optimum conditions for alumina preparation were determined and are as follows: reaction at 55 ºC for 1.5 h, the concentration of sodium meta aluminate is 0.4 mol/L, the dose of surfactant is 0.3%. The product can be effectively purified by washing with 25% acetic acid, and then characterized by laser particle size distribution, X-ray fluorescence spectrometry (XRF), X-ray diffraction (XRD) and scanning electron microscopy (SEM). Results prove that the product is γ-Al 2 O 3 with particle diameters in the range of 0.6-0.9 µm, and its degree of purity is 98.7%.

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