SUMMARY BackgroundHepatitis C virus infection evolves into chronic progressive liver disease in a significant percentage of patients. Monocytes constitute a diverse group of myeloid cells that mediate innate and adaptive immune response. In addition to proinflammatory CD16+ monocytes, a Tie-2+ subgroup -Tie-2 expressing monocytes (TEMs) -that has robust proangiogenic potential has been recently defined.
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