Our results showed pINS-related structural abnormalities in FD patients, indicating that GM and WM parameters were not affected independently. These findings would lay the foundation for probing an efficient target in the brain for treating FD.

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In this paper, a novel local time-step scheme for hybrid time-domain method combing finite difference and Cell-Centered finite volume method is put forward. This scheme leads to satisfied results and high efficiency with no special requirement for meshes. The principles of the hybrid method and numerical schemes are described and applied to solve three dimensional electromagnetic scattering problems. Two numerical results are given to compare this method with the FDTD alone in terms of accuracy and memory requirement for a solution with a given accuracy. They are also compared with the results obtained by using MOM. It is shown that the presented method is more accurate and efficient.

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