When the cerebrovascular patology exists, the interstitial fluid decreases. Because of that the area of the brain decreases and the area of the ventricles increases.

Because of the long usage of obsidane the cerebrum liquid’s flow-out to the one of the brain hemisphere breaks and also local edema of the brain en-larges.

The usage of the lymphotrope therapy in patients’ with cerebrovasculas pathology complex treatment helps to readjustment of neurons’ pericellular habitat out of bilirubine and prevent the development of repeated abnormalities of cerebral circulation.

The aim of the research was studying the features of neurohumoral regulation of carbohydrate metabolism in experimental diabetes mellitus. A model of diabetes mellitus was created by introducing 0.1% solution of epinephrine hydrochloride into animals. Biochemical parameters of carbohydrate metabolism (cortisol, C-peptide and glucose) were studied in 17 animals on day 0, 15, 21, 30, 45. On the same day morphofunctional changes formed in the pancreas and Nodi lymphatici pancreaticoduodenales were studied. With stress, there is an increase in cortisol and C-peptide and a decrease in the concentration of glucose in the blood. In distress cortisol secretion is reduced, and the production of C-peptide and glucose concentration in the blood increases. In the lymph nodes formed functional changes that led to a violation of cellular and humoral immunity in the body. Conclusion. The cause of diabetes is a failure in the work of self-regulating mechanisms of carbohydrate metabolism, which leads to dysregulation pathology of the autonomic nervous system, manifested by antagonism between adrenaline and cortisol, insulin and cortisol.

In the experiment on rabbits were presents, that experimental arterial hypertension didn’t led to functional failure of lymphatic drainage of brain. On the background of beta-blocker obzidan use failure liquor outflow from brain took place.