The use of gold nanorods for photoacoustic molecular imaging with simultaneous multiple targeting is reported. Multiple targeting is done by utilizing the tunable optical absorption property of gold nanorods. This technique allows multiple molecular signatures to be obtained by simply switching laser wavelength. HER2 and EGFR were chosen as the primary target molecules for examining two cancer cells, OECM1 and Cal27. Both in vitro and in vivo mouse model imaging experiments were performed, with contrast enhancement of up to 10 dB and 3.5 dB, respectively. The potential in improving cancer diagnosis is demonstrated.

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As children approach middle childhood and adolescence, the influence of fathers on children's behavior and development becomes more equivalent to that of mothers. The quality of father-child attachment operates as a stronger predictor of adolescents' cognitive and emotional development. During adolescence, symbolic communication by means of the Internet becomes increasingly more important than physical approximate-seeking behavior in infancy and childhood. Adolescents might regard the Internet as their new attachment figure or may seek new attachment figures through the Internet. This study was designed to address the impacts of father-adolescent attachment on adolescents' Internet use. Seven hundred twelve adolescent participants completed questionnaires to assess the associations among their paternal attachment, intensity of Internet use, and Internet services preference. The result revealed that alienation positively predicted pathological Internet use (PIU) directly and also indirectly mediated by leisure services preference. Trust predicted PIU negatively. These results help to provide parents and educators with guidance in adolescents' more appropriate Internet use.

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