Infrastructure planning in most cities is a process of sectoral implementation which produces independent sectoral solutions to urbanisation issues. With the advent of sustainable practices, along with the challenges posed by climate change, cities are discovering important synergies among urban infrastructure sectors which are being used to reduce the urban footprint. In the need for sustainable infrastructure, the city of Frankfurt am Main, although operating in a sectoral manner, has learned from past experiences and has progressively developed a collaborative approach to infrastructure planning. This collaborative approach increases the possibilities for trans-sectoral projects and reduces the consumption of natural resources. This paper showcases interesting sectoral and trans-sectoral projects in the infrastructure sectors of energy, water, wastewater, solid waste and urban agriculture. The showcased projects have been selected from a study of 36 operational, programmatic and educational initiatives implemented by the city.