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Isothermal amplification Á Low costDear Editor, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a major threat for mankind and poses a great challenge to global economy. On 31 st December 2019, the World Health Organization (WHO) was informed about a cluster of pneumonia cases in Wuhan, China [1]. Subsequent investigations identified a completely unique sequence of coronavirus which differed from existing type SARS-CoV known as SARS-CoV-2. Initially, it was observed within the Wuhan province of China but later spread fast to rest of the world, which forced WHO to declare COVID-19 as pandemic. So far there is a total of 10,302,867 confirmed cases, with 505,518 global deaths, while 5,558,161 are recovered cases. In India, a total of 5,68,473 confirmed cases out of which 2,15,838 of active cases and 3,35,656 of recovered cases also 16,919 of the death cases are reported till date. The SARS-CoV-2 is a single-stranded, positive-sense RNA