Background: Coronavirus Disease 2019 (COVID-19) Pandemic is still spreading rampantly in almost every country in the world, causing around 1.5 million dead at the point of time, and the death rate is still going up even though inoculation of vaccine has started. It is widely recognized that this pandemic Covid-19 is caused by infectious pathogens from the animal. Aim: This study investigates the relationship of biodiversity loss and zoonotic disease pandemic. The main reason for this migration is habitat (biodiversity) loss which is primarily caused by deforestation. Subject and Methods: Using Pooled Ordinary Least Square (POLS) models and worldwide data collected by using biodiversity in 170 countries. Results: It was found that biodiversity loss is positively related to the emergence of contagious disease. Conclusion: This verifies once for all that deforestation must be controlled so that the chance of emergent of next pandemic is mitigated.

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