These findings suggest that GPR30 mediates the nontranscriptional effect of estrogen on the activation of PI3K/Akt pathway in endometrial cancer cells.

Cry1Ie is encoded by cry1Ie, a gene that is silent in Bacillus thuringiensis strains but can be over-expressed in Escherichia coli. A protease-resistant core form of Cry1Ie with a molecular weight of approx. 55 kDa was found among the products of trypsin digestion. The oligomer and monomer of the protease-resistant core form were purified separately. The oligomer fraction contained a small quantity of dimer and a large amount of aggregates larger than tetramers. The 50% lethal concentrations (LC(50)) of the full-length Cry1Ie and both the monomer and oligomer fractions of the protease-resistant core form against Plutella xylostella were 14, 21 and 1400 microg/ml, respectively.

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Food safety accidents occur frequently, which has caused great harm to people’s health. With the consideration that food quality requires the joint efforts of all members of the food supply chain and that quality-improving efforts for food have a positive external effect, we focus on the quality-improving effort level, which is very important for food quality and safety. This paper builds an evolutionary game model and employs the replicated dynamic equation to study evolutionarily stable strategies of suppliers and producers. Furthermore, simulation experiments are conducted to verify the modeling analyses and demonstrate the influences of game parameters. The research results show that the behavioral strategies are closely related to the factors such as the ratios of the input to the output, the cost of quality-improving efforts, the hitchhiking benefits, and the initial strategy. Only when the punishing dynamics of the government exceeds a certain value, both participants can choose the quality-improving effort strategy. Based on the results, this paper has provided some inspiration for policy-making of government institutions.