Background: The objective of the study was to determine the awareness and attitude towards HPV vaccination among medical and nursing students. Methods: A descriptive cross sectional study was done among nal MBBS part 2 and nal year BSC nursing students with a pretested questionnaire about HPV vaccine. Results: About 79.3% students were aware of the availability of HPV vaccine.69.8% knew the correct age of vaccination.25.8% of the students have been vaccinated with HPV vaccine. About 72.4% students were willing to advice or receive vaccine which was more among medical students compared to nursing students(p value<0.05). High cost and inadequate information were stated as the main obstacle preventing vaccination. Conclusion: Lack of awareness among medical and paramedical students can be detrimental to the health of society. So, there is need to increase awareness and improve vaccination status among future health care providers against Human papilloma virus