No abstract

Orthodontic treatment is more complicated when both soft and hard tissues must be considered because an impacted maxillary canine has important effects on function and esthetics. Compared with extraction of impacted maxillary canines, exposure followed by orthodontic traction can improve esthetics and better protect the patient's teeth and alveolar bone. Therefore, in order to achieve desirable tooth movement with minimal unexpected complications, a precise diagnosis is indispensable to establish an effective and efficient force system. In this report, we describe the case of a 31-year-old patient who had a labio-palatal horizontally impacted maxillary left canine with a severe occlusal alveolar bone defect and a missing maxillary left first premolar. Herein, with the aid of three-dimensional imaging, sequential traction was performed with a three-directional force device that finally achieved acceptable occlusion by bringing the horizontally impacted maxillary left canine into alignment. The maxillary left canine had normal gingival contours and was surrounded by a substantial amount of regenerated alveolar bone. The 1-year follow-up stability assessment demonstrated that the esthetic and functional outcomes were successful.

To identify different quality control of Silybin powder for injection, some indexes such as loss on drying, insoluble particle, ignition dregs, content determining were analyzed.The results indicated that regression curve of Silybin powder for injection was Y = 47741X+531.19, r = 0.999 9. Precision: average peak area was 11182.42, RSD was 0.4796%(n = 6); Stability: RSD was 1.030 9%, which indicated its good stability in 14 hours. The average recovery rate was 99.84%, RSD was 0.5935%. Sample content determination: Content of all samples was as much as 95%-105% of claimed values. The average sample content was 40.7499 mg/bottle. All indexes fit in with pharmacopoeia, which indicate the quality of this Silybin powder for injection can be efficiently controlled.Silybin; powder for injection; quality control; content determination (key words)