Objectives: This study aimed to investigate the survival outcomes and poten tial prognostic factors of patients with temporal bone squamous cell carcinoma (TBSCC) treated at our institution. Methods:We retrospectively included patients who were diagnosed with TBSCC between 2008 and 2019. The Kaplan-Meier (KM) method was used to describe overall survival (OS), and the association between baseline characteristics and prognoses was examined using Cox proportional hazards models.Results: Fifty consecutive patients with TBSCC were included in this study. The results showed that patients with advanced modified Pittsburgh (MPB) T classi fications had a poorer prognosis (T3 vs.