Background The northeastern region of Argentina has the highest age-adjusted cervical cancer mortality rates. Given the strong link between HPV infections and cervical cancer, one of the main interventions is the population-based use of HPV vaccines. However, the acceptability is not very clear in low-and middle-income countries. The purpose of this study was to estimate the level of HPV vaccine acceptance and associated determinants among caregivers of girls in a northeastern city of Argentina. Methods A school-based survey was conducted in 2015 using a multistage sampling method. The primary sample unit were schools stratified by socioeconomic status selected at random, and caregivers of school girls were interviewed. The acceptability was determined using the adapted Theory of Planned Behavior. We performed logistic regression models to assess associated determinants. Results The study included 347 caregivers. The intention to vaccinate was 59.88%. A positive attitude of caregivers (aOR 4.67; 3.11-7.03) and positive influence of social norms (aOR 1.95; 1.03-3.70) were the main predictors independently associated to the intention to vaccinate against HPV. In contrast, practicing a Christian non-Catholic religion decreased the intention to vaccinate against HPV (OR 0.59; 0.36-0.95). All other factors evaluated were not significantly associated with intention to vaccinate against HPV.
El estadio adulto del nematode Dioctophyme renale habitualmente parasita el riñón derecho del perro y de varios mamíferos domésticos y silvestres, aunque a veces aparece en otros órganos o tejidos. El propósito de este trabajo fue reportar el hallazgo de ejemplares adultos y huevos de D. renale en las cavidades corporales de un canino hembra, de raza indefinida y 18 meses de edad. El animal fue hallado sin vida por el propietario, quien solicitó la realización de una necropsia para descartar o confirmar un posible envenenamiento. La necropsia reveló la presencia de dos ejemplares adultos del parásito, uno en la cavidad abdominal y otro en la cavidad torácica. Este último medía 40 cm de longitud x 10 mm de diámetro. En la pleura mediastínica se verificó la existencia de 12 orificios de 20 a 50 mm de diámetro. Los pulmones mostraban lesiones focales que resultaron más numerosas en el lóbulo medio derecho que en el resto de los lóbulos; los cortes histológicos revelaron la presencia de abundantes estructuras compatibles con huevos de D. renale en la superficie pleural, donde también se constataron varias áreas con intensa respuesta inflamatoria. Los hallazgos histopatológicos caracterizaron la existencia de una pleuritis granulomatosa multifocal.
Triatoma infestans (Klug) (Hemiptera: Reduviidae) is the main vector of Chagas disease in the Southern Cone of America and resistance to pyrethroid insecticides has been detected in several areas from its geographical distribution. Pyrethroid resistance presents a complex geographical pattern at different spatial scales. However, it is still unknown if the toxicological variability is a common feature within villages of the Gran Chaco were high resistance was descripted. The objectives of this study were to determine: (a) the microgeographical distribution of the deltamethrin-resistance in insects from Pampa Argentina village, (b) the performance of the insecticide impregnated paper bioassay to evaluate deltamethrin-resistance in field collected insects and (c) the lethal activity of the fumigant canister containing DDVP against insects resistant to deltamethrin. High survival of T. infestans exposed to discriminant dose was observed in the samples of all the evaluated dwellings, suggesting that the resistance to deltamethrin is homogeneous at the microgeographical level. Resistance determination by impregnated paper bioassay was similar to traditional topical determination, highlighting the use of this rapid methodology in field large-scale monitoring. The fumigant canister was not effective against resistant insects, remarking the need to develop suitable formulations that ensure minimal toxicological risk and high effectivity.
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