Patients with intrauterine adhesions may exhibit serious medical problems such as infertility and miscarriage. In this study, we aimed to evaluate the clinical efficacy of hysteroscopic surgery combined with extensive care during the preoperative, intraoperative and postoperative phase of the procedure by professional nursing teams in the management of patients with intrauterine adhesions. 98 patients with intrauterine adhesions enrolled from October 2013 to June 2016 were randomly divided into a control group (49 cases) who received drug therapy and an observation group (49 cases) who underwent hysteroscopic surgery combined with extensive care during the preoperative, intraoperative and postoperative phase of the procedure. Our data showed that the conception rate in observation group (85.7%) was significantly higher than that of control group (59.2%) (P=0.033). Additionally, the abortion rate (0.0%) and the incidence of postoperative complications (8.2%) in the observation group was significantly lower than those in the control group (3.4% and 8.2%) (P<0.05). Moreover, satisfaction scores in observation group (100%) is significantly higher than that in the control group (81.6%) (P=0.026). Furthermore, there is significant less anxiety or depression in the observation group than in the control group (P<0.05). Together, we find that hysteroscopic surgery combined with extensive care during the preoperative, intraoperative and postoperative phase of the procedure by professional nursing teams considerably improve the clinical outcomes of patients with intrauterine adhesions.