Background: A quality system in a clinical laboratory involves supervision of all the phases of the total testing process: pre-analytical, analytical, and post-analytical. Misinterpretations during the last phase may cause a wrong diagnosis. Aim: Improvement of the interpretation of test results in the laboratory of biochemistry - CHU Batna, by the introduction of computer software ensuring better delivery and interpretation of results. Method: The updating of the reference values was based on the biochemistry analysis guides and equipment method sheets used in the biochemistry laboratory. The development of the software used two programs, Visual Basic 6 for the interface and Access 2007 for setting up the database. The first version of the software includes only general biochemistry. Results and Discussion: The analysis report obtained by the software developed presents specific reference values to each patient, and allows a record of results as an electronic file that can be archived and/or sent directly to the requesting service in the case of the presence of an intranet. In the future, the development of this first version of the software will focus on the introduction of tumor markers and hormonology with regular reviews of the reference values.