Sr-In intermetallics were studied by first-principles calculations within density functional theory (DFT) with the projector augmented-wave technique (PAW) and the generalized gradient approximations (GGA) as implemented in the ABINIT code. Six intermetallics: SrIn5, SrIn3, SrIn2, SrIn, Sr5In3 and Sr3In were investigated in their observed experimental structures. The lattice constants, enthalpies of formation and bulk modulus of the Sr-In intermetallics have been calculated. The calculated lattice constants and enthalpies of formation are in good agreement with experimental and other theoretical results.