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Glucose-sensitive microcapsules, whose volume changed in response to glucose, were successfully prepared by encapsulating glucose oxidase (GO x ) into poly(L-lysine-alt-terephthalic acid) (PPL) microcapsules. The GO x PPL microcapsules decreased in size in a glucose solution, after a certain lag time. The shrinking rate of the capsules showed a linear correlation with glucose concentration, while the lag time showed a logarithmical correlation with the glucose concentration.Glucose-responsive materials are of interest as insulin delivery systems.

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We investigated the aggregation state of a mixed monolayer of 1,2-dimyristoyl-sn-glycero-3-phospholine and cholesterol at different surface pressures by AFM. AFM images revealed a nanoscopically separated structure despite a macroscopic homogenization of the monolayer under compression.