Swiftlet nest is edible bird’s nest (EBN). Edible bird’s nest contain EGF (Epidermal Growth Factor) that has a role in skin cell regeneration. This research aims to find out the effect of the hydrocarbon and absorption bases on the edible bird’s nest ointment (Aerodramus fuciphagus) from the physical character of each ointment. The edible bird’s nest ointment made into two formula with hydrocarbonand absorption bases. Each ointment tested of the physical characteristics include organoleptic test, homogenity test, pH test, spreading test, sticky test, and viscosity test. The data obtained was analyzed statistically using T Independent Test. The result showed that there was affect the hydrocarbon and absorption bases to the physical characteristics of edible bird’s nest ointment include spreadability (P 0,011), sticky (P 0,020), and viscosity, but there was not affect to organoleptic, homogenity and pH of edible white bird’s nest ointment (Aerodramus fuciphagus).
Edible bird's nest (Aedrodramus fuchipagus) contains EGF (Epidermal Growth Factor) and sialic acid which is useful in wound healing. The aim of this study was to investigate the effect of edible bird's nest on the injured Alloxan-induced rats to form optimal ointment formulation of edible bird's nest (Aedrodramus fuchipagus) which can heal wounds. The method used in this research is experimental using 25 Sprague Dawley rats divided into 5 groups in which each group consists of 5 rats; Group I was the control group (Vaseline + Betadine®), Group II, III, and IV were the group of EBN + Betadine® with concentrations of 10%, 20%, and 30%; and Group V was of the Sanoskin Meladerm® (SM) + Betadine® group. The rats were modeled for diabetes by inducing Alloxan (150mg/kgBW/i.p) and exposed with DM when the blood sugar level was > 200 mg/dL. The back skins were sliced as long as 2 cm and 2 mm depth and were given treatment according to the group, 1 x daily for 10 days. Parameters that were noticed were length wound, length of the dry wound, and the number of days of scab formation. The results obtained in the control group were 10%, 20%, and 30% on the EBN group, and the SM group on the 9th day were 1.3±0.2449, 0.34±0.427, 0.56±0.4586, 0±0, 0±0. The results of the average length of the dry wound in the control group were 10%, 20%, and 30% on the EBN group, and the SM group were 1±0.5, 2±1.5, 4±0, 8, 1±0.8, and 2±0.63. While the result of the average day of scab formation on the control group was 10%, 20%, and 30% on the EBN groups, SM Groups were 1.3±0.47, 2.2±1.6, 3.8±0.8, 1±0, and 2±0.63. Based on Kruskal Wallis test, there were significant differences in the wound length among treatment groups (sig 0.013) and significant differences in dry wounds among treatment groups (sig 0.046), but there was no difference in the time of scab formation among treatment groups (sig 0.066). In conclusion, edible bird’s nest (Aedrodramus fuchipagus) ointment concentration of 30% is the most optimal ointment to wound healing in Alloxan-induced male rats when compared to Sanoskin Melladerm.
Dewasa ini, pembinaan program pendidikan kesehatan dan pelayanan kesehatan di usia sekolah terutama di tingkat sekolah dasar sudah mulai berkembang. Untuk menyempurnakan pembinaan pendidikan kesehatan dan pelayanan tersebut perlu juga adanya apoteker cilik yang nantinya bisa saling berdampingan. “Aku Apoteker Cilik” merupakan suatu kegiatan pengenalan profesi kefarmasian kepada anak-anak usia dini sehingga dapat mengenal dan menumbuhkan minat kepada profesi kefarmasian. Kegiatan pengabdian masyarakat ini dilaksanakan di Sekolah Dasar Negeri 4 Sungai Besar, Banjarbaru, Kalimantan Selatan. Kegiatan Pengabdian Masyarakat ini dilakukan dengan pengisian materi seputar pengenalan sosok profesi Apoteker serta tugasnya. Media yang digunakan adalah LCD, banner, alat peraga apoteker, dan perangkat aplikasi kefarmasian. Setelah pengisian materi, dilakukan juga games dan kegiatan aplikasi kefarmasian untuk mengetahui pemahaman peserta didik. Peserta didik paling aktif dijadikan sebagai maskot apoteker cilik. Kegiatan telah dilaksanakan pada hari Jumat/02 September 2016 pada pukul 08.00 WITA. Rundown kegiatan diawali dialog pengantar dengan menggunakan alat peraga profesi kesehatan dokter dan apoteker. Selanjutnya dilakukan penyajian video “Tahu Nggak Sih?” seputar sosok dan tugas apoteker. Disesi berikutnya dilakukan penyampaian materi terkait dunia kefarmasian dan sosok & tugas apoteker serta games. Dilanjutkan penyajian video “Peracikan Obat” dan kegiatan aplikasi kefarmasian. Disesi akhir dilakukan pemilihan peserta didik paling aktif sebagai maskot apoteker cilik. Kata Kunci: Apoteker, Apoteker cilik, Banjarbaru
The edible nest swiftlets are suspected to contain sialic acid that can increase the process of cell growth that can reduce the formation of scar tissue and accelerate wound healing. This study aimed to determine the effect and the optimal dosage of edible nest swiftlets ointment on skin histopathology of diabetes mellitus rats that suffered a scratch wound. This study used 25 male white rats, divided into 5 groups, all groups were treated with betadine and the intervention of group 1 was vaseline only (control group), group 2, 3, and 4 were edible nest swiftlets (ENS) ointment with 10%, 20%, and 30% concentration and group 5 were the sanoskin as control positive. The rats were injured in the back area and given the treatment according to the group once a day for 14 days. Skin tissue was taken to make histopathologic preparations for observation on the 0th, 7th, and 14th days. The parameters observed included the number of macrophages, neo-capillarization, and fibroblasts. The result on the 14th day showed that the number of macrophages in the control group, sanoskin group, and ENS 10%, 20%, and 30% group was 3.8±5.019; 3.2±2.489; 1.84±2.387; 1.8±2.049 and 1.2±1.095. The result of neocapillilization were 1.28±1.673; 1.4±1.673; 2.8±1.778; 5.4±4.159; and 15±30.773. The conclusion showed there was a significant difference and there was the effect of edible nest swiftlets ointment on the number of macrophages, the number of neocapillilization, and the density of fibroblasts on the rats with diabetes mellitus that suffered a scratch wound.
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