Education in the 21st century aims to change the learning paradigm from teacher-centered to student-centered in order to improve student learning outcomes. Hence, a learning model is needed to improve the students' ability to solve problems by paying attention to their academic ability. This study aims to determine the effect of using the student academic ability-based problem solving and 5E cycle learning models on the student learning outcomes in addictive materials and addictive substances. This study used an experimental method with a 2x2 factorial design. The population in this study was all students of grade VIII SMPN 18 Padang. This study's sample was chosen using the purposive sampling technique, the data collection techniques for the student learning outcomes used to test techniques at the end of learning. The data analysis was performed by using the prerequisite tests (normality and homogeneity tests) and the hypothesis tests using 2-way ANOVA and continued with Bonferroni advanced test. The results show that:  There is an interaction between the problem-solving model and the academic ability-based 5E Cycle learning model on the student learning outcomes, but there is no significant difference in learning outcomes between the problem-solving model and the 5E learning cycle model. There is an effect on the academic ability towards the student learning outcomes. There is no difference in the student learning outcomes between students with high academic ability in the two sample classes. There is no difference between the students with low academic ability in the two sample classes.

The research problem at Junior High School 29 Padang is the science learning process that takes place centered on the teacher, the low learning competency of the students, has not used a learning model that contains sains literacy, and low scientific literacy skills. Efforts that can be done are applying the problem solving learning model with scientific literacy. This research was conducted at Junior High School 29 Padang in material of KD 3.6 about additives and addictive substance. This research is an experimental research using the Randomized Control Group Posttest Only Design. The study population was all grade VIII students of Junior High School 29 Padang. Sampling was taken by using purposive sampling technique. Class VIII.3 as the experimental class and class VIII.5 as the control class. The instruments used in the form of posttest questions, observation sheets. The research instrument used was a test of learning outcomes. The research instrument used was a test of learning outcomes. The results of the t test were known that in the knowledge competency tcount> t table (3,02>1.67). the attitude competency tcount> t table (5.38>1.67) and the skills competency tcount> t table (4,39>1.67). This showed that the hypothesis was accepted. So, it can be concluded that the application of a problem solving model with scientific literacy on additives and addictive substance can improve the competency of knowledge, attitudes, and skills of Junior High School 29 Padan students.