The plasma-ionized calcium levels decreased during haemodialysis when a dialysate calcium concentration of 5 mg/100 ml was used. When dialysis was performed with a bath calcium concentration of 7.5 mg/100 ml, there was a significant increase in the plasma-ionized calcium levels in the post-dialysis period. These results are discussed in relation ot the optimal dialysate calcium concentrations and development of dialytic bone disease.

Abstract:A new Schiff base ester, 4-{[(3-chlorophenyl)imino]methyl}-3-hydroxyphenyl myristate, was synthesized and its IR, 1 H NMR, 13 C NMR and MS spectroscopic data are presented.

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1. Administration of 2-thiophenecarboxylic acid to rats maintained on a low calcium diet resulted in a significant depression in the serum levels of total and ionized calcium and inorganic phosphate. 2. The serum magnesium levels were not altered by the drug.