The current study conducted an online survey to understand the challenges and needs teachers face for identifying and nurturing students with twice exception. Among 896 respondent schools, 179 schools were reported to have 277 identified 2E students. The results indicated that schools with both gifted and disability classes/programs or services identified more 2E students than did schools without a special education program. Although increasing the awareness and knowledge of general education teachers is beneficial for the identification of 2E students, most of the respondents reported that they need gifted education teachers to get involved in developing students’ talents. Obvious opportunity gaps existed between schools with only disability education and with gifted and disability education. An effective support system with manpower and financial assistance from governments is also essential for closing opportunity gaps and meeting the needs of both learners and teachers.