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Spontaneous regression of cancers is extremely rare and is associated with specific malignancies. Spontaneous regression of bronchogenic lung cancer has rarely been reported, and regression of small cell lung cancer is even less common. Such regression is generally ascribed to immunological factors but is not well understood. This case report describes a patient with spontaneous regression of small cell lung cancer that has persisted for 11 years and considers possible mechanisms.

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Multi-membered N-heterocycles R 0690An Efficient Solution Phase Synthesis of Triazadibenzoazulenones: "Designer Isonitrile Free" Methodology Enabled by Microwaves. -A concise two-step solution-phase synthesis of title compounds (V) is achieved through a microwave-promoted four-component condensation to form bisamides of type (VI) followed by TFA-promoted cyclocondensation. The process does not require the use of a specially designed isonitrile. -(HULME*, C.; CHAPPETA, S.; GRIFFITH, C.; LEE, Y.-S.; DIETRICH, J.; Tetrahedron Lett. 50 (2009) 17, 1939-1942; BIO5 Inst., Coll. Pharm., Univ. Ariz., Tucson, AZ 85721, USA; Eng.) -Mais 32-171