Our results showed that the dynamic thiol-disulfide homeostasis of the neonate was greatly influenced by the way of delivery and supported that vaginally delivered infants have less oxidative stress.

Objective The mental, physical and sexual health of women as well as maternal and fetal health should be considered during the prenatal and postnatal periods. Investigating the effect of clinical Pilates exercises and prenatal education (CPE & PE) on obstetric and neonatal outcomes as well as the mental, physical, and sexual health of women was intended. Methods In the second trimester, mothers with singleton pregnancies who attended (n=79, study group) or did not attend (n=80, control group) CPE & PR were recruited to this prospective cohort study, and were evaluated in the prenatal and postnatal periods. Depression was assessed with Beck Depression Inventory (BDI), sexual functions with Female Sexual Function Index (FSFI), muscle strength with Gross Muscle Scales (GMS), and labor pain with Visual Analogue Scale (VAS). In addition, the presence of low back pain (LBP) was questioned. Results No significant association of CPE & PE with obstetric outcomes such as cesarean rates, preterm birth, and neonatal outcomes such as birth weight and Apgar scores were identified. Changes in VAS scores, the incidence of perineal trauma, and episiotomy were not associated with CPE & PE. However, CPE & PE was associated with lower BDI scores, a gradual increase in the total scores of FSFI, increased GMS, and reduced LBP. Conclusion CPE & PE had no adverse effects on obstetric and neonatal outcomes and was associated with improved mental, physical, sexual health scores during pregnancy and postpartum.

No abstract

Objective: The aim of this study is to investigate the incidence, risk factors, clinical presentation, management, morbidity and mortality of ectopic pregnancy (EP) by evaluating all cases treated in a tertiary care center in Ankara. Methods: A total of 1243 cases were retrospectively studied who were diagnosed with ectopic pregnancy during the clinical course and were treated in the early pregnancy unit between January 2014 and December 2018. Demographic information from hospital records, e.g., risk factors, ultrasound findings, initial and followed up b-hCG levels, and treatment methods (followed up, medical, and surgical) were recorded. Results: The incidence of EP was 7 per 1000 pregnancies. The mean age was 30.64±5.71 years. The most common risk factors for EP were previous abdominal surgery (37.8%) and previous miscarriage (28.6%). Eighty-three (22%) of patients diagnosed between 2013 and 2014, 129 (34.2%) of patients diagnosed between 2015 and 2016, and 165 (43.8%) of patients diagnosed between 2017 and 2018 had a history of Cesarean section. Seventy-seven (6.2%) cases were followed up, 487 (39.2%) were treated surgically, and 772 (62.1%) were treated with methotrexate. Conclusion: Delivery by Cesarean section is a risk factor for the development of EP. Cesarean section has been shown to be an important factor in the increase of the incidence of EP over the years. As a result of this increase, new treatments have been developed and conservative surgical or drug treatments have been initiated. Close monitoring of the current literature evaluating ectopic pregnancies and treatment according to this literature will decrease mortality and morbidity rates.

Amaç: Serum albumini iskemik olaylara yanıt olarak değişir ve N-terminalinin kobalt metaline afinitesi azalır. Bu modifikasyon sonucu iskemi modifiye albümin (IMA) oluşur. IMA, iskemik olaydan hemen sonra yükselir ve iskeminin sonlanmasından sonra birkaç saat yüksek kalır. Bu çalışmanın amacı, doğum şeklinin annelerde ve term bebeklerde İMA düzeylerine etkisini araştırmak ve hangi doğum şeklinin daha fazla oksidatif strese neden olduğunu belirlemektir. Gereç ve yöntem: Vakalar doğum şekline göre vajinal doğum grubu (VD, n=40) ve sezaryen grubu (C/S, n=40) olarak gruplandırıldı. Annelerden doğum öncesi, kordon kanından ve bebeklerden doğumdan sonraki 24. saatte serum örnekleri belirlenen kriterlere uyan vakalardan alındı; (1) tekil canlı doğum, (2) gebelik yaşı 37-41 6/7 hafta arası, (3) 2500 ve 4000 gr doğum ağırlığı ve (4) 5. dakikada Apgar skoru ≥ 8. Her iki grubun İMA düzeyleri karşılaştırıldı. Bulgular: Doğum öncesi serum IMA seviyeleri iki grup arasında benzerdi. Kordon kanı IMA düzeyleri C/S grubunda VD grubuna göre anlamlı olarak yüksekti (0,694±0,113'e vs 0,642±0,084, p=0,021). C/S ile doğan bebeklerde serum IMA seviyeleri, VD ile doğan bebeklere göre daha yüksekti, ancak sonuç istatistiksel olarak anlamlı değildi. Sonuç: Bulgularımız bebeklerde ve kord kanında IMA düzeylerinin doğum şeklinden etkilenebileceğini ve VD ile doğan bebeklerde oksidatif stresin azaldığını desteklemektedir.