Bacterial infections remain the leading cause of death in children, the elderly, and immunocompromised patients. Andrographolide (AG), the main active component of the herb <i>Andrographis paniculata</i>, has been used for many years for anti-inflammatory and antibacterial infections. AG has an antibacterial effect on a wide variety of bacteria, which is reflected in the inhibition of bacterial pathogenic factors and the regulation of immunity to downregulate infectious inflammation caused by bacteria. In the current climate of frequently occurring antibiotic resistance, AG might be considered a promising lead for new antibacterial drug development. This review outlines the therapeutic potential of AG and its analogs in combating various bacterial infections, focusing on the mechanisms of action.

No abstract

No abstract

Studies have demonstrated that partial discharge in SF 6-insulated electrical equipment can cause SF 6 decomposition, resulting in the generation of various products. Quantitative detection of these decomposition products can be used to evaluate the state of the equipment's insulation. The use of optical methods for detecting the products has many advantages, such as high precision, fast response, and sample reusability. Thus far, optical detection methods have been applied for detection of SF 6 decomposition products, and a few promising results have been obtained. We review the various optical technologies for detection of SF 6 decomposition products, introduce their principles and applications, and summarize some recent research progress. In addition, we propose two optical detection technologies that can be applied in this field.