The project had shown that pre- and post-implementation audits represent a useful method for translating evidence into practice. The conduct of this project showed that achieving change in clinical practice was challenging. It also showed that positive audit results were achieved through the enthusiasm, commitment and dedication of every member of the project team, the use of champions who were involved in direct patient care and performance feedback.

This project utilised the process of audit, feedback and re-audit cycle as a strategy to improve clinical practice. It demonstrated the feasibility of translating evidence-based practice into the clinical setting, with remarkable improvement in maintaining patency of central venous access devices for patient with cancer. Finally, it is evidenced that the commitment and enthusiasm of team members and all the registered nurses in maintaining the patency of central venous access devices were the crucial factors for the success of this project. The support and assistance provided by the stakeholders also played an important role in the sustainment of the project.