No abstract

Personal protection is critical for firefighters to ensure their safety in an extreme fire environment. However, conventional firefighter uniforms tend to focus on thermal protection and have the bottleneck of lacking personal thermal management. The heat stress caused by poor thermal management inevitably detriments human body health. Here, a hump‐inspired hierarchical fabric (HHF) composed of hierarchical insulation structure and directional water transport is demonstrated for personal thermal protection and thermal comfort management. The results show that the HHF exhibits enhanced thermal insulation ability and endows continuous one‐way liquid flow through distributed sweat‐wicking channels. Compared to conventional firefighter uniform fabrics, HHF shows simultaneously low thermal conductivity (0.0192 W m−1 K−1) in the cross‐plane direction and high breathability and moisture permeability. It is observed that the temperature and relative humidity of the simulated skin covered‐HHF uniform at extreme condition (≈80 °C) are ≈20.6 °C and ≈13.6% lower than that of conventional firefighter uniforms. It is expected that the HHF fabric with exceptional thermal performance can make a significant impact on future development of advanced protection uniform for firefighters.

No abstract

Solar steam generation (SSG) in a green way for desalination is a promising application, but reaching a high-efficiency and salt-rejecting SSG is still challenging, especially in hypersaline brine. Herein,...

Myocardial ischemia/reperfusion (MI/R) injury is a complex phenomenon that causes severe damage to the myocardium. However, the potential molecular mechanisms of MI/R injury have not been fully clarified. We identified potential molecular mechanisms and therapeutic targets in MI/R injury through analysis of Gene Expression Omnibus (GEO) database. Differentially expressed genes (DEGs) were found between MI/R injury and normal samples, and overlapping DEGs were found between GSE61592 and GSE67308. Gene Ontology (GO) and pathway analysis were performed for overlapping DEGs by Database for Annotation, Visualization and Integration Discovery (DAVID). Then, a network of protein-protein interaction (PPI) was constructed through the Search Tool for the Retrieval of Interacting Genes (STRING) database. Potential microRNAs (miRNAs) and therapeutic small molecules were screened out using microRNA.org database and the Comparative Toxicogenomics database (CTD), respectively. Finally, we identified 21 overlapping DEGs related to MI/R injury. These DEGs were significantly enriched in IL-17 signaling pathway, cytosolic DNA-sensing pathway, chemokine signaling, and cytokine-cytokine receptor interaction pathway. According to the degree in the PPI network, CCL2, LCN2, HP, CCL7, HMOX1, CCL4, and S100A8 were found to be hub genes. Furthermore, we identified potential miRNAs (miR-24-3p, miR-26b-5p, miR-2861, miR-217, miR-4251, and miR-124-3p) and therapeutic small molecules like ozone, troglitazone, rosiglitazone, and n-3 polyunsaturated fatty acids for MI/R injury. These results identified hub genes and potential small molecule drugs, which could contribute to the understanding of molecular mechanisms and treatment for MI/R injury.