With the development of large‐scale and high‐resolution TFT‐LCD display products, higher requirements are put forward for display quality. Fine Pitch, cpd coupled horizontal stripe, and head shaking mura are several types of mura that have great impact on display quality. The relationship of pixel arrangement structure and display mura is analyzed in this paper. The advantages and disadvantages of several common pixel arrangements are summarized and some methods to avoid display mura are proposed.