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There is a positive correlation between reported ingested dose of paracetamol and subsequent chance of a PPC being above a defined treatment line; however, ingested dose of paracetamol alone is a poor risk assessment tool in accurately determining need for treatment with an antidote.

Objective: To assess the ability of end-tidal capnography to provide continuous ventilatory monitoring in sedated, non-intubated ED patients following sedative overdose. Methods: Observational study undertaken in a tertiary hospital ED. Patient ventilation was assessed using capnography over 60 min. Results: Capnography provided uninterrupted monitoring for 99% of total study time. Capnography detected all episodes of hypoxia detected by SpO 2 monitoring. Changes in capnography preceded 70% of hypoxic episodes detected by SpO 2 . There were no major adverse events or incidents of device failure. Conclusion: Capnography provided reliable measurement of ventilatory function in sedated non-intubated, poisoned ED patients.

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