Background: Shoulder pain is a common musculoskeletal disorder prompting many patients to seek treatment. Acupotomy is a common treatment for shoulder which has been widely used in hospitals. But its efficiency has not been scientifically and methodically evaluated. This protocol aims to evaluate the efficacy and safety of acupotomy for treating shoulder pain. Methods: Relevant studies will be searched from the databases of PubMed, EMBASE, Cochrane Library, China Knowledge Resource Integrated Database, Weipu Database for Chinese Technical Periodicals, SinoMed, and Wanfang Database. Two researchers will independently select studies, collect data, and assess the methodology quality by the Cochrane risk of bias tool. Results: The systematic review will provide high-quality evidence to assess the efficacy and safety of acupotomy for shoulder pain as well as adverse events. Conclusion: The systematic review will provide evidence to assess the effectiveness and safety of acupotomy therapy for shoulder pain patients. INPLASY registration number: INPLASY 202130002.

With the development of new information technologies such as cloud computing, Internet of Things, and mobile Internet of Things, Industry 4.0, Smart Manufacturing and Made in China 2025 have been proposed as the main content of the development of the next industrial revolution. In order to realize these projects with the common characteristics of intelligence, service, and green, a new manufacturing model, digital twin, is proposed, which combines the digital twin with industrial systems, that is, the industrial control virtualization system. However, due to the frequent occurrence of industrial control system security incidents in recent years, the industrial control virtualization system is vulnerable to attacks. The industrial control system is huge and cumbersome. Once attacked, it will cause consequences that affect the whole body. In response to this problem, this article carried out a research on DoS attack detection methods for Modbus TCP in OpenPLC, using OpenPLC as a tool for industrial control system virtualization, building a digital twin system with Raspberry Pi, and launching DoS attacks on the system, combined with Snort Intrusion detection is carried out, and the experimental results show that the built digital twin system can detect DoS attacks in OpenPLC.

Service composition is a key issue in the pervasive computing systems ofservice orientation. Automatically converting web services composition plans into BPEL4WS is an essential step in SASO (Semantic and Automatic Service Orchestration system). In this paper, we employ DAG to represent web services composition plans, and propose an automatic conversion algorithm BPELGEN which automatically converts the DAG into BPEL4WS through dynamic code generation at runtime. There are three main characteristics of the algorithm.(1) automatically converting web services composition plan into BPEL4WS, (2) supporting nestedflow process generation; (3) the BPEL4WS generated by the algorithm satisfying data dependency and execution dependency ofthe composition plan.

T h i s systematic review aims to evaluate the effectiveness of acupotomy for shoulder pain. Is acupotomy a safe treatment for shoulder pain? Condition being studied: Shoulder pain is a common disease that reduced range of motion, which seriously affects the quality of life of patients. Current conventional treatments include non-pharmacological measures, medication, and surgical INPLASY 1

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