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The present study describes one titrimetric and two spectrophotometric methods for the determination of fexofenadine hydrochloride (FFH) in bulk drug and in tablets based on bromination of FFH by bromine generated in situ by the action of acid on bromate-bromide mixture. In titrimetry, FFH is treated with a known excess amount of bromate-bromide mixture in acid medium followed by the determination of unreacted bromine iodometrically (method A). In spectrophotometry, the residual bromine is determined by its reaction with excess iodide and the liberated iodine (I 3 ̶ ) is either measured at 360nm (method B) or iodine reacted with starch followed by the measurement of the blue colored starch-iodide complex at 570nm (method C). Titrimetry allows the determination over the range of 4.5-30.0mg FFH whereas in spectrophotometry, Beer's law is obeyed in the concentration ranges of 2-20.0 and 0.6-6.0μg mL -1 FFH for method B and method C, respectively. The molar absorptivities are calculated to be 2.2x10 4 and 5.3x10 4 L mol -1 cm -1 for method B and method C, respectively, and the corresponding Sandell sensitivity values are 0.0238 and 0.0101µg cm -2 . The limits of detection and quantification are also reported for both the spectrophotometric methods. The proposed methods were applied successfully to the determination of FFH in raw material and commercial tablets. Statistical comparison of the results was performed using Student's t-test and F-ratio at 95% confidence level and there was no significant difference between the official and proposed methods with regard to accuracy and precision. Further, the validity of the proposed methods was confirmed by recovery studies via standard addition technique.