Probiotics are “live strains of strictly selected microorganisms which, when administered in adequate amounts, confer a health benefit on the host”. After birth, our intestine is colonized by microbes like Escherichia coli, Clostridium spp., Streptococcus spp., Lactobacillus spp., Bacteroides spp., and Bifidobacterium spp. Our intestine is an extremely complex living system that participates in the protection of host through a strong defence against external aggregations. The microbial ecosystem of the intestine includes many native species of Bacteroides and Firmicutes that permanently colonize the gastrointestinal tract. The composition of flora changes over time depending upon diet and medical emergencies which leads to the diseased condition. Probiotics exert their mode of action by altering the local environment of the gut by competing with the pathogens, bacteriocins production, H2O2 production etc. Obesity is one of the major health problems and is considered as the most prevalent form of inappropriate nutrition. Probiotics like Lactobacillus Sp., Bifidobacterium Sp., Streptococcus Sp. are successfully used in the treatment of obesity proved in clinical trials. Faecal microbiota transplant (FMT), also known as a stool transplant, is the process of transplantation of Faecal bacteria from a healthy donor into a recipient’s gut to restore normal flora in the recipient. The therapeutic principle on which FMT works is microbes and their functions and metabolites produced by them which are used to treat a variety of diseases. The present review focuses on the role of gastrointestinal microbiome, probiotic selection criteria, their applications and FMT to treat diseases.

This study is related to the outbreak of COVID 19 pandemic in India, how the widespread of this virus has forced individuals to be locked in our homes which has drastically affected the growth of our economy. Not only India, the world is facing the COVID 19 catastrophe which has shut down all the professionals and business enterprises. Since the COVID 19 is a very contagious virus and it is incurable till date and curable with limited scope, hence WHO published the advisory stating that till the pandemic is dealt with every individual must maintain social distance in order to slow down the rate of spread of COVID 19. In this world of technological advancement and better traveling equipment, the world is nothing but a global village and since, if one part of the economy is getting affected, it has a large scale impact on all over the world. However, “Janta Curfew” has been implemented, it has become more challenging for the employees to visit workplaces. The study will detail about analysing the aspect of work from home facilities during the lockdown period. (The data is based on during the first lockdown period from March to June)